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KMID : 1130620060020030202
Journal of Clinical Neurology
2006 Volume.2 No. 3 p.202 ~ p.205
Primary Diffuse Leptomeningeal Gliomatosis: Report of a Case Presenting with Chronic Meningitis
Kim Sung-Hun

Jun Dong-Chul
Park Jin-Se
Heo Jae-Hyeok
Kim Sung-Min
Kim Ju-Han
Paek Sun-Ha
Kim Man-Ho
Abstract
Neoplastic meningitis occurs in approximately 5% of patients with cancer. Primary diffuse leptomeningeal gliomatosis is a rare condition whereby a glioma arises from heterotopic cell nests in the leptomeninges. We report here a case presenting with clinical features similar to those of chronic infectious meningitis without positive cerebrospinal fluid cytology. Neurological signs in our patient deteriorated progressively without responding to antitubercular, antiviral, or antibiotic therapy. Leptomeningeal biopsy sampling revealed the condition to be primary diffuse leptomeningeal gliomatosis
KEYWORD
Primary Diffuse Leptomeningeal Gliomatosis, Chronic Meningitis
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